Oddly enough, science and beauty have become allies in a field some professionals refer to as "cosmeceuticals." The term was coined by Albert Kligman, the University of Pennsylvania researcher credited with discovering the effectiveness of Retin-A, a vitamin A, in smoothing aging skins.
—Jackie White, "On the face of it," Kansas City Star, January 25, 1998

Under controlled laboratory conditions, Factor X produces changes in the skin fibroblasts, the building blocks of the skin, that can be seen visually and can be measured biochemically. Thus Factor X could be among the first of a new kind of cosmetic, a 'cosmeceutical,' that actually changes the cell biology with beneficial effects on aging of cells. The product would work on the skin from the inside-out, rather than outside-in, like most present cosmetics.
—"Senetek anti-aging compound passes acute toxicology tests," Business Wire, October 14, 1987