Many venture-capital investors believe that out of a portfolio of ten investments, only two will be "moon rockets" — ventures that produce a big payoff with a successful initial public offering.

There are very few moon rockets," says Bill Bygrave, a professor of entrepreneurship at Babson College in Wellesley. "The moon rockets are the Microsofts, Lotuses and Intels, the ones that start with the intent to get very big quickly because they're in a very big potential market. The typical business is not a moon rocket. Most enter very small niches.

Finally to Zeneca which has stopped giving the impression of a moon-rocket and begun to establish a chart with an identifiable uptrend.